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Daniel C Javitt Selected Research

Glycine (Aminoacetic Acid)

2/2015Behavioral and cognitive effects of the N-methyl-D-aspartate receptor co-agonist D-serine in healthy humans: initial findings.
8/2013Glycine treatment of the risk syndrome for psychosis: report of two pilot studies.
4/2013Glycine site agonists of the N-methyl-D-aspartate receptor and Parkinson's disease: a hypothesis.
12/2012Effects of novel, high affinity glycine transport inhibitors on frontostriatal dopamine release in a rodent model of schizophrenia.
9/2012Twenty-five years of glutamate in schizophrenia: are we there yet?
1/2012Glycine transport inhibitors in the treatment of schizophrenia.
7/2009Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modification.
4/2009GABAB/NMDA receptor interaction in the regulation of extracellular dopamine levels in rodent prefrontal cortex and striatum.
3/2009Adjunctive glycine in the treatment of obsessive-compulsive disorder in adults.
1/2008Glycine transport inhibitors and the treatment of schizophrenia.
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Daniel C Javitt Research Topics

Disease

85Schizophrenia (Dementia Praecox)
11/2022 - 03/2002
12Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 08/2010
8Cognitive Dysfunction
01/2020 - 10/2007
5Neurobehavioral Manifestations
06/2012 - 07/2002
4Treatment-Resistant Schizophrenia
03/2005 - 03/2002
3Major Depressive Disorder (Major Depressive Disorders)
01/2021 - 07/2006
3Substance-Related Disorders (Drug Abuse)
12/2016 - 01/2003
2Mental Disorders (Mental Disorder)
02/2015 - 07/2011
2Tardive Dyskinesia
04/2013 - 04/2004
2Parkinson Disease (Parkinson's Disease)
04/2013 - 05/2012
2Sleep Initiation and Maintenance Disorders (Insomnia)
07/2010 - 06/2009
1Chronic Disease (Chronic Diseases)
01/2021
1Neurodevelopmental Disorders
10/2019
1Hallucinations (Hallucination)
07/2019
1Inflammation (Inflammations)
01/2019
1Infections
01/2019
1Hypertension (High Blood Pressure)
12/2016
1Prodromal Symptoms
05/2015
1Treatment-Resistant Depressive Disorder
04/2013
1Alzheimer Disease (Alzheimer's Disease)
04/2012
1Alcoholism (Alcohol Abuse)
06/2009
1Narcolepsy
06/2009
1Confusion (Bewilderment)
06/2009
1Sleepiness
06/2009
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
03/2009

Drug/Important Bio-Agent (IBA)

28N-Methylaspartate (NMDA)IBA
01/2019 - 07/2002
26N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2022 - 07/2002
22Glycine (Aminoacetic Acid)FDA LinkGeneric
02/2015 - 07/2002
14Antipsychotic Agents (Antipsychotics)IBA
01/2022 - 03/2002
14Serine (L-Serine)FDA Link
01/2018 - 07/2002
13Phencyclidine (Angel Dust)IBA
12/2012 - 01/2003
12Glutamate Receptors (Glutamate Receptor)IBA
05/2015 - 12/2002
11Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2008
10Glutamic Acid (Glutamate)FDA Link
01/2022 - 01/2007
10Dopamine (Intropin)FDA LinkGeneric
01/2019 - 02/2004
8KetamineFDA LinkGeneric
10/2020 - 02/2004
8Cycloserine (Seromycin)FDA Link
04/2013 - 03/2002
7Pharmaceutical PreparationsIBA
01/2019 - 04/2004
4Clozapine (Clozaril)FDA LinkGeneric
01/2019 - 01/2004
4Olanzapine (Zyprexa)FDA Link
11/2013 - 03/2002
4Amphetamine (Amfetamine)FDA LinkGeneric
12/2012 - 02/2004
4Hallucinogens (Psychedelics)IBA
10/2010 - 01/2007
3gamma-Aminobutyric Acid (GABA)IBA
01/2021 - 06/2009
3Risperidone (Risperdal Consta)FDA LinkGeneric
03/2005 - 03/2002
2Protons (Proton)IBA
01/2019 - 02/2014
2(4- (3- fluoro- 5- trifluoromethylpyridin- 2- yl)piperazin- 1- yl)(5- methanesulfonyl- 2- (2,2,2- trifluoro- 1- methylethoxy)phenyl)methanoneIBA
08/2017 - 12/2016
2Neurotransmitter Agents (Neurotransmitter)IBA
06/2014 - 05/2008
2davunetideIBA
06/2013 - 04/2012
2Temazepam (Nocturne)FDA LinkGeneric
04/2011 - 08/2009
24-hydroxybutyric acidIBA
07/2010 - 06/2009
2Therapeutic UsesIBA
06/2009 - 05/2008
2Amino AcidsFDA Link
09/2005 - 04/2004
1Serotonin (5 Hydroxytryptamine)IBA
01/2022
1metabotropic glutamate receptor 2IBA
10/2020
1Cholinergic ReceptorsIBA
01/2020
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2020
1Glycine Dehydrogenase (Decarboxylating)IBA
10/2019
1Biological ProductsIBA
10/2019
1salicylhydroxamic acid (SHAM)IBA
07/2019
1Acetylcysteine (Siran)FDA LinkGeneric
01/2019
1Chlorpromazine (Thorazine)FDA Link
01/2019
1Glutathione (Reduced Glutathione)IBA
01/2019
1Hormones (Hormone)IBA
01/2019
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2019
1VitaminsIBA
01/2019
1Cholinergic Agents (Cholinergics)IBA
01/2019
1Prednisolone (Predate)FDA LinkGeneric
12/2018
1Excitatory Amino AcidsIBA
01/2018
1Hemoglobins (Hemoglobin)IBA
12/2016
1AntibodiesIBA
03/2015
1N 30IBA
09/2014
1Kynurenic Acid (Kynurenate)IBA
07/2014
1N-acetylaspartate (N-acetyl aspartate)IBA
06/2013
1Choline (Choline Chloride)IBA
06/2013
1Antidepressive Agents (Antidepressants)IBA
04/2013
1R231857IBA
12/2012
1Excitatory Amino Acid AgonistsIBA
09/2012
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
09/2012
1Peptides (Polypeptides)IBA
04/2012
17- (1,1- dimethylethyl)- 6- (2- ethyl- 2H- 1,2,4- triazol- 3- ylmethoxy)- 3- (2- fluorophenyl)- 1,2,4- triazolo(4,3- b)pyridazineIBA
03/2011
1GABA-A Receptors (GABA(A) Receptor)IBA
03/2011
1Aminobutyrates (Aminobutyric Acid)IBA
03/2011
1Anesthetics (Anesthetic Agents)IBA
10/2010
1Designer DrugsIBA
10/2010
1SaltsIBA
07/2010
1SodiumIBA
07/2010
1Illicit Drugs (Recreational Drugs)IBA
06/2009
1Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
06/2009
1ParvalbuminsIBA
05/2008
1NicotineFDA Link
05/2008
1DysbindinIBA
03/2008

Therapy/Procedure

3Transcranial Direct Current Stimulation
11/2022 - 07/2014
3Therapeutics
10/2019 - 07/2006
1Surgical Instruments (Clip)
01/2021
1Neurofeedback
01/2017
1Cognitive Training
01/2017
1Transcranial Magnetic Stimulation
01/2016
1Electrodes (Electrode)
07/2014
1Critical Care (Surgical Intensive Care)
06/2014
1Aftercare (After-Treatment)
08/2013